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The effect of L-Methionine supplementation on the immune responses and performance during ultra-endurance exercise

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dc.contributor.advisor Rogers GG en
dc.contributor.advisor Rossouw J en
dc.contributor.author Harden LM en
dc.date.accessioned 2016-09-22T11:20:01Z
dc.date.available 2016-09-22T11:20:01Z
dc.date.created 2000 en
dc.date.submitted 2002 en
dc.identifier.uri http://hdl.handle.net/20.500.11892/111994
dc.description.abstract This double-blind placebo controlled study investigated the effect of daily supplementation with glutathione precursors (L-Methionine, vitamin B6, vitamin B12, folic acid and magnesium) on the incidence of upper-respiratory tract infections (URTIs) and race performance in ultra-marathon runners. The incidence of URTIs was recorded in twenty-one (males n = 17 and females n = 4) runners during their preparation for (76 days) and recovery from (84 days) an ultra-marathon race. During the preparation period the incidence of URTI was 36% in the supplement group and 80% in the placebo group which was not significant (p = 0.08). The supplement group did however loose in total less training days (23 days) than the placebo group. This did not result in the supplement group running faster race times than the placebo group but it probably resulted in the supplement group significantly (p = 0.05) improving on their previous race times by 41 ± 60 min. The incidence of respiratory symptoms during the 3 weeks post race was 27% in the supplement group and 40% in the placebo group, which was not significantly different (p = 0.65). In conclusion, this study has failed to demonstrate a clear relationship between supplementation with glutathione precursors (L-Methionine, vitamin B6, vitamin B12, folic acid and magnesium) and upper respiratory tract infection. There was evidence suggesting that supplementation can reduce the number of days lost due to illness and thereby improve the optimal design of training programmes and ultimately performance. en
dc.language English en
dc.subject Medical sciences: Physiology en
dc.subject Motor functions and integument en
dc.title The effect of L-Methionine supplementation on the immune responses and performance during ultra-endurance exercise en
dc.type Masters degree en
dc.description.degree MSc en


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